诚信为本巅峰首选

张琨(Zhang Kun)
副教授
电子邮件:kunzhang@sjtu.edu.cn
办公地点:印刷厂楼315

研究方向

研究领域: 环境分析监测,环境污染物行为,环境健康

现阶段主要研究方向:

  • 环境中新污染物的分析监测及其来源和环境行为解析
  • 环境中未知污染污染物的非靶标筛查和鉴定
  • 环境污染物质对健康,特别是对神经发育的影响

个人简历

  • 2003-2007 北京大学,城市与环境诚信为本巅峰首选 环境科学,理学学士
  • 2007-2012 北京大学,城市与环境诚信为本巅峰首选 环境地理学,理学博士
  • 2012-2015 加拿大阿尔伯塔大学,实验医学与病理学系,博士后
  • 2015-2016 瑞士西北应用科技大学,生态环境研究所,博士后
  • 2017-2018 美国哈佛大学医诚信为本巅峰首。呒堆芯恐

研究成果

主要致力于环境新污染物的环境行为和生物学效应研究。利用气相/超高效液相质谱联用检测技术结合体外微粒体暴露,微生物降解,PBPK模型模拟,野外样品采集分析等方式对环境污染物质的来源降解、不同结构食物网生物富集差异、药代行为学特征及其生态毒理学效应开展了系统研究工作。同时,利用超高分辨质谱非靶向检测技术结合生物模拟和鱼体暴露等方法开发了对环境中复合有机污染物毒性和生物富集性评估的新方法体系,并将其成功应用于油砂废水等复杂场景中优先控制污染物名单筛查。以上研究成果共发表SCI论文40余篇,其中第一/通讯作者SCI论文19篇 (Environ. Sci. Technol. 10篇,Environ. Sci. Technol. Lett. 1篇,Environ. Int. 1篇)。先后主持上海市浦江人才计划项目、国家自然科学基金项目等科研项目。荣获林超地理学奖学金、陶氏可持续发展创新挑战赛优秀奖。

代表性论著

  1. Zuo, S. Q.; Meng, H. Y.; Liang, J. H.; Zhen, H. J.; Zhu, Y.; Zhao, Y. B.; Zhang, K.*; Dai, J. Residues of Cardiovascular and Lipid-Lowering Drugs Pose a Risk to the Aquatic Ecosystem despite a High Wastewater Treatment Ratio in the Megacity Shanghai, China. Environ. Sci. Technol. 2022, 56 (4), 2312-2322.
  2. Shen, J.; Shi, H. C.; Zhao, Y. B.; Fent, K.; Zhang, K*. Large-Scale Transcriptional Profiling of Molecular Perturbations Reveals Cell Line Specific Responses and Implications for Environmental Screening. Environ. Sci. Technol. 2021, 55 (22), 15266-15275.
  3. Zhang, K.; Liang, J. H.; Brun, N. R.; Zhao, Y. B.*; Werdich, A. A. Rapid Zebrafish Behavioral Profiling Assay Accelerates the Identification of Environmental Neurodevelopmental Toxicants. Environ. Sci. Technol. 2021, 55 (3):1919-1929.
  4. Zhao, Y.; Liang, J.; Meng, H.; Yin, Y.; Zhen, H.; Zheng, X.; Shi, H.; Wu, X.; Zu, Y.; Wang, B.; Fan, L.; Zhang, K*. Rare Earth Elements Lanthanum and Praseodymium Adversely Affect Neural and Cardiovascular Development in Zebrafish. Environ. Sci. Technol. 2021, 55 (2):1155-1166.
  5. Zhao, Y. B.; Zhang, K.*; Xu, X. T.; Shen, H. Z.*; Zhu, X.; Zhang, Y. X.; Hu, Y. T.; Shen, G. F. Substantial changes in nitrogen dioxide and ozone after excluding meteorological impacts during the COVID-19 outbreak in mainland China. Environ. Sci. Technol. Lett. 2020, 7, 402-408. (Highlight, High Cited)
  6. Zhang, K.; Zhao, Y. B.* Reduced Zebrafish Transcriptome Atlas toward Understanding the Environmental Neurotoxicants. Environ. Sci. Technol. 2018, 52 (12), 7120-7130.
  7. Zhang, K.; Zhao, Y.; Fent, K. Occurrence and ecotoxicological effects of free, conjugated and halogenated steroids of 17α-hydroxypregnanolone and pregnanediol in Swiss wastewater and surface water. Environ. Sci. Technol. 2017, 51 (11), 6498–6506.
  8. Zhang, K.; Wiseman, S. B.; Giesy, J. P.; Martin, J. W. Bioconcentration of Dissolved Organic Compounds from Oil Sands Process-Affected Water by Medaka (Oryzias latipes): Importance of Partitioning to Phospholipids. Environ. Sci. Technol. 2016, 50 (12), 6574–6582.
  9. Zhang, K.; Pereira, A. S.; Martin, J. W. Estimates of Octanol–Water Partitioning for Thousands of Dissolved Organic Species in Oil Sands Process-Affected Water. Environ. Sci. Technol. 2015, 49 (14), 8907-8913.
  10. Zhang, K.; Wan, Y.; Jones, P. D.; Wiseman, S.; Giesy, J. P.; Hu, J. Y. Occurrences and Fates of Hydroxylated Polybrominated Diphenyl Ethers in Marine Sediments in Relation to Trophodynamics. Environ. Sci. Technol. 2012, 46 (4), 2148?2155.





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